A Brisbane man has been charged with murder after allegedly throwing an elderly man from a first floor balcony.

Police were called to the School Road unit in Yeronga at about 1.40pm on Sunday after reports of a disturbance.

A 74-year-old Yeronga man sustained serious head injuries after hitting the concrete in the attack and was transported to the Princess Alexandra Hospital where he later died.

A 49-year-old local man, who police say was not known to the elderly man, was detained at the scene and has been charged with one count of murder.

He will appear in the Brisbane Magistrates Court on Monday.

—AAP