A woman has given birth after doctors restored her fertility using frozen ovarian tissue removed when she was nine years old.
The BBC has reported that Moaza Al Matroosh, 24, is believed to be the first woman in the world to have a baby after having an ovary frozen and then restored.
“It’s like a miracle,” Ms Al Matrooshi told the BBC.
“We’ve been waiting so long for this result — a healthy baby.”
Her doctor, Sara Matthews, a consultant in gynaecology and fertility, said the birth provided hope for others needing treatment for conditions such as cancer, blood or immune disorders that negate their fertility.
“This is a huge step forward. We know that ovarian tissue transplantation works for older women, but we’ve never known if we could take tissue from a child, freeze it and make it work again.”
Ms Al Matrooshi, from Dubai, was born with beta thalassaemia, a fatal inherited blood disorder if untreated.
Requiring chemotherapy before receiving a bone-marrow transplant from her brother, Ms Al Matrooshi had one of her ovaries removed and had the tissue frozen.
Fragments of her ovarian tissue were mixed with cryo-protective agents and slowly reduced in temperature to minus 196C, before being stored under liquid nitrogen, the BBC reported.
Danish surgeons in 2015 transplanted five pieces of the frozen tissue back into her body, four of which were stitched on to her failed left ovary and one to the side of her uterus.
To enhance their chances of conceiving, Ms Al Matrooshi and her husband underwent IVF treatment.
From eight eggs collected, three embryos were produced, two of which were implanted earlier this year.