The disappearance of a large cash inheritance and $70,000 in loans from Adelaide woman Ann Smith’s bank account has sparked further investigations, police have revealed.

The discovery is one of a number of “financial irregularities” found after Ms Smith, who had cerebral palsy, died of profound septic shock and multiple organ failure in April.

Police believe the 54-year-old, who was also suffering from malnutrition, may have spent up to a year sitting in a cane chair prior to her death.

They launched a manslaughter investigation last month, and this week made a public appeal for information about missing jewellery and fridges, and the use of her car.

In the latest development in the case, police on Saturday revealed two separate loans totalling $70,000 were taken out in Ms Smith’s name in the last six years.

The loans, taken out from “small lending companies”, were supposedly to allow her to travel and buy a new car, but were not used for either of those purposes.

Investigating officer Detective Senior Sergeant Phil Neagle said it was “most unlikely” Ms Smith had obtained the loans by herself.

“They were significant loans,” he said.

“We know she did not travel or buy a new car after they were taken out, but the money is now gone.”

A large cash inheritance left to Ms Smith by her parents in 2009 had also been withdrawn from her bank account.

Investigators acknowledged some of the money would have been used for Ms Smith’s day-to-day expenses, but said “the total amount is disproportionate with [Ms Smith’s] lifestyle”.

“Ann may well have spent some of the money herself, but we are now trying to ascertain how much, and if any has been unlawfully removed from her account, and where it went,” Detective Senior Sergeant Neagle said.

Police said Ms Smith was known to be generous to her friends and it was possible her kindness may have been exploited.

Detective Superintendent Des Bray said Crime Stoppers had received 10 calls since police appealed for information regarding Ms Smith’s 1998 Silver Honda Accord sedan yesterday.

During their investigation, investigators discovered there was no refrigerator or nutritional food in Ms Smith’s home.

Food found inside the house included potato chips, packet soups, chocolate and soft drink, as well as pasta with an expiry date of 2014.

Police also found a near-full tube of toothpaste with an expiry date of 2017, and said Ms Smith was unable to clean her own teeth.

-with agencies