A man is dead and six people, including two children, have been injured in a head-on collision at Coffs Harbour on NSW’s north coast.

The 58-year-old was killed when a Nissan Pulsar and Ford Falcon collided on Hogbin Drive just before 1pm on Saturday, police say.

The man, a rear passenger in the Falcon, was taken to Coffs Harbour Health Campus but died a short time later.

The driver of the Pulsar – a 31-year-old woman – was taken to hospital with leg and wrist injuries.

Among her passengers, a nine-year-old girl and five-year-old boy were also hospitalised with serious injuries.

The 59-year-old female driver of the Falcon suffered multiple fractures to her arms and legs.

And a 19-year-old man, a passenger in the Falcon, was taken to hospital with internal injuries.

An investigation into the circumstances surrounding the crash is underway with police urging witnesses to come forward.