Some of William Tyrrell’s relatives do not think they will see the boy again.

Tyrrell went missing from his grandparents’ home in Kendall, New South Wales, in September 2014, allegedly snatched while playing in a Spiderman costume.

He is yet to be found, despite constant police investigation, with a string of false leads frustrating authorities.

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Breaking her silence about Tyrrell’s disappearance, 56-year-old Natalie Collins heartbreakingly revealed that she does not think her grandson is still alive.

“I wish he was alive, but I don’t think he is,” Ms Collins told The Daily Telegraph.

Ms Collins admits the disappearance has had a profound impact on her life – and that the search for William has ‘killed everyone’ over the last 18 months.

“There are times when I just haven’t wanted to live. It has been hell,” she added.

“With William gone, I couldn’t even concentrate. I just kept crying and crying about the whole thing.

“I couldn’t even get out of bed. I couldn’t work.

“Every night we would watch the news. It has killed me inside. It has killed everyone.

“It’s just a damn mess. This is the best it gets. It’s just like this every day.”

An unnamed family member, also quoted by The Daily Telegraph, believes a paedophile ring are responsible for Tyrrell’s disappearance.

“Everything I read in the media about a paedophile ring… it’s like reading a book of what I thought happened,” he said.

Anyone with information on William Tyrrell’s disappearance is urged to contact Crime Stoppers on 1800 333 000.