A Melbourne man has been charged with murder after a three-year-old boy died in hospital.

The boy was taken to the Royal Children’s Hospital with life-threatening injuries on Friday afternoon after emergency services were called to a Glenroy address.

He later died in hospital.

Brok Hughes, 25, was interviewed by police and charged with one count of murder.

He faced an out-of-sessions hearing early on Saturday and has been remanded to appear at the Melbourne Magistrates Court later in the day.