Hollywood star George Clooney has been taken to hospital after he was involved in a high-speed motorcycle collision with a car in Sardinia, Italy.

According to a representative for the actor, 57-year-old Clooney was treated and released from hospital with minor injuries in Olbia, where he is filming his latest TV series, Catch-22.

Reports suggest Clooney was travelling at 65 mp/h (105 kp/h) slammed into and smashed the car’s windshield after it failed to give way. He allegedly suffered minor injuries to his leg.

Photos taken at the scene of the accident showed a banged-up black scooter on the road with a dark blue station wagon with a broken windshield facing the other way.

Ambulance personnel tend to a man lying on the ground, later identified as actor George Clooney, after being involved in a scooter accident. Photo: AAP

“He is recovering at his home and will be fine,” the spokesperson said.

The star confirmed to CNN that he was traveling at 65 miles per hour before the head-on impact and that “it’s good to be alive.”

The TMZ website reported that the crash was more dramatic than originally thought.

It reported Clooney was thrown 20 feet (6 metres) through the air and his helmet cracked on impact as it shattered the car’s windshield, which said it confirmed the details with Clooney’s representative.

“At 8.15am George Clooney was riding his scooter on the State Road 125 towards Olbia from Puntaldia,” an Italian police spokesman said in a statement.

“A car (a Mercedes E SW) did not respect the right of way and hit him. George Clooney fell and slammed the windshield of the Mercedes.

“The car driver called the 112, the emergency number of Carabinieri, and they sent the Municipal Police, an ambulance and the Fire Department.

“[The] MRI was negative, and he is not seriously injured. George Clooney has already been discharged and he stays well.”

Local newspaper La Nuova Sardegna reported Clooney’s wife Amal, a human rights lawyer, rushed to be at his side in hospital.

Amal and the couple’s children are thought to be staying in San Teodoro, Sardinia during filming.

Clooney was treated at John Paul II hospital in Olbia on the Sardinia island.

It isn’t the first time the actor has been injured in a motorcycle accident – in New Jersey in 2008 he broke his ribs while his then-girlfriend Sarah Larson suffered a broken foot.

-with agencies