Two South African winners of the Nobel Peace Prize have urged Israel and the Palestinians to negotiate peace, with former archbishop Desmond Tutu comparing the regional crisis to apartheid.

Their comments came as Pretoria condemned Israel’s ground offensive into the Gaza strip and several prominent South Africans of Jewish descent called for the country to cut ties with Israel.

“It is not a Muslim or Jewish crisis. It is a human rights crisis with roots to what amounts to an apartheid system of land ownership and control,” Tutu said at a news conference for the annual summit of peace prize winners.

Fellow Nobel prize winner and former president FW de Klerk said Israel and the Palestinians needed to work for peace.

“For the Israelis and Palestinians, the lesson to be learnt from South Africa is that there is no dispute which cannot be resolved by meaningful negotiation if there is the will on both sides to negotiate,” said De Klerk, the last white president of South Africa, who will co-host the Nobel summit with Tutu.

The feisty cleric, who won the prize in 1984 and has drawn the apartheid analogy in the past, said the latest flare-up in the Middle East crisis was the result of a void in global leadership.

“As an old man, my appeal to my fellow laureates and peacemakers is to step into the leadership void, to make your voices heard from all corners of the globe, to advocate or pressure your government and institutions to cajole, to persuade,” Tutu said.

Speaking on the day former president and peace prize winner Nelson Mandela would have turned 96, Tutu said helping to overcome what he called “the greatest peace challenge of our times” would be a fitting tribute to the late South African leader.